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SISU Co Q10 100mg Softgels
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SISU Co Q10 100mg Softgels

SISU Co Q10 100mg Softgels

SISU Co Q10 100mg Softgels Details

SISU Co Q10 100mg Softgels deliver 100mg of ubiquinone CoQ10 — the most-researched form of Coenzyme Q10 with decades of human studies behind it. CoQ10 is essential for cellular energy production in every tissue, with particular concentration in the heart muscle. Production declines with age starting in the 30s–40s, making supplementation increasingly important for cardiovascular health, energy, and antioxidant protection. Particularly important for anyone on statin medications, which deplete CoQ10. SISU sources their CoQ10 from sugar beet fermentation — a clean, vegan-compatible source. Available in 60 or 120 softgels. Made by SISU.

Vitamins Lowest Prices | Lowest Price in Canada — Guaranteed | Ships from Ontario across Canada

Quick Facts

Brand SISU (Canadian)
Form Ubiquinone (most-researched form of CoQ10)
Per softgel 100mg CoQ10
Source Sugar beet fermentation
Sizes 60 or 120 softgels
SISU lineup also 30mg, 60mg, vegetarian capsules, ubiquinol (active form)
Best taken With food containing some fat for absorption

Who SISU Co Q10 100mg Is For

  • Adults 40+ noticing energy decline who want cellular energy support
  • People taking statin medications — statins deplete CoQ10 and supplementation is widely recommended
  • Adults focused on cardiovascular wellness (CoQ10 has strong heart research)
  • People with mild heart conditions wanting natural support alongside medical care
  • Active adults seeking energy and recovery support at the cellular level
  • Anyone with family history of cardiovascular concerns wanting daily preventative support
  • People who want the well-researched ubiquinone form at accessible pricing

Who this product is NOT for: If you're under 35 with no specific reason to take CoQ10, you may not need supplementation — the body produces adequate CoQ10 in younger adults. People on blood thinners (warfarin) should consult their healthcare practitioner; CoQ10 may slightly reduce warfarin effectiveness. Pregnant or breastfeeding women should consult their practitioner. If you specifically want the active reduced form (better absorbed by some), look at ubiquinol products (like SISU Ubiquinol QH 100mg) — higher-priced but may be better for older adults whose conversion is impaired. If you're very price-sensitive, generic CoQ10 products cost less but SISU's quality control is consistent.

Vitamart's Take

CoQ10 is one of the better-researched cardiovascular nutrients, with decades of studies for heart health and energy. Your body makes its own CoQ10, but production drops starting in your 30s — by 80, you have roughly half what you had at 25. SISU's CoQ10 is the workhorse choice: ubiquinone (the most-researched form), 100mg per softgel (the clinical research dose), at one of the better per-softgel costs in Canada. If you're on a statin, this is one of the most important supplements to add — statins deplete CoQ10.

How SISU Co Q10 Compares

SISU Co Q10 (Ubiquinone) vs SISU Ubiquinol QH

Ubiquinone is the oxidized form — most-researched, more accessible, body converts it to active ubiquinol. Ubiquinol is the reduced active form — better absorbed for older adults (60+) or people with impaired conversion. SISU makes both. For adults under 60 with no specific reason for ubiquinol, ubiquinone (this product) is the sensible choice. For older adults or those who haven't responded to ubiquinone, ubiquinol may work better.

SISU Co Q10 100mg vs SISU 30mg or 60mg

SISU makes CoQ10 at three doses (30mg, 60mg, 100mg). 30mg is the maintenance dose for younger adults; 60mg is mid-range; 100mg is the typical therapeutic dose used in heart research and recommended for statin users. Choose based on your goal. For statin support, 100–200mg daily is the research range. For general daily maintenance in middle age, 60–100mg works.

SISU Co Q10 100mg vs Generic CoQ10

Generic CoQ10 (drugstore brands) often uses synthetic CoQ10 at low doses with poor absorption — lower cost but you may absorb minimal active CoQ10. SISU uses naturally-fermented CoQ10 in softgel format with reliable absorption. The cost difference is modest; the absorption difference is meaningful.

SISU Co Q10 vs PQQ

PQQ (pyrroloquinoline quinone) is a related compound sometimes paired with CoQ10 for cellular energy support. PQQ may help create new mitochondria (the cellular energy factories); CoQ10 supports function of existing ones. Different roles. Some advanced cardiovascular routines use both; for most people, CoQ10 alone is the foundation.

What CoQ10 Actually Does

  • Cellular energy production. CoQ10 is essential for the energy-producing machinery in your cells (the mitochondria) that produces ATP — cellular energy. Without CoQ10, energy production stalls. Every cell in your body needs CoQ10; tissues with high energy demands (heart, brain, muscles, kidneys) need the most.
  • Powerful antioxidant. CoQ10 is one of the few antioxidants your body makes natively. It protects cell membranes and LDL cholesterol from oxidative damage. Particularly important for cardiovascular tissues exposed to constant oxidative stress.
  • Production declines with age. The body's ability to make CoQ10 peaks in the 20s and declines steadily. By age 80, you typically have around half the CoQ10 of your younger years. This decline correlates with reduced cellular energy and increased oxidative stress in aging tissues.
  • Heart muscle concentration. Heart muscle has higher CoQ10 concentration than any other tissue in the body — because the heart never stops working and needs constant energy. Cardiovascular research on CoQ10 covers heart failure, blood pressure, post-heart-attack recovery, and statin-related muscle pain.
  • Statin depletion. Statin medications (atorvastatin, simvastatin, rosuvastatin, etc.) block the same biochemical pathway used to make CoQ10. Statin users often have significantly reduced CoQ10, which is implicated in the muscle pain and fatigue some statin users experience. CoQ10 supplementation is widely recommended for statin users by integrative cardiologists.
  • Difficult to get from food. CoQ10 is found in small amounts in beef, peanuts, sardines, and other foods, but the amounts are far below what you'd get from supplementation. Cooking also destroys CoQ10. For meaningful intake, supplementation is the practical approach.
  • Why softgels. CoQ10 is fat-soluble — it absorbs significantly better from oil-based softgels than dry capsules. The softgel format is the gold standard for CoQ10 supplementation.
  • Ubiquinone vs ubiquinol. The body has both forms at the same time — ubiquinone (oxidized) and ubiquinol (reduced/active) — with continuous interconversion. Younger adults convert ubiquinone to ubiquinol efficiently. Older adults and people with certain conditions may have impaired conversion, in which case ubiquinol supplementation skips the conversion step.

How To Use

Adults: Take 1 softgel daily with food containing some fat for best absorption. For higher therapeutic doses (statin support, heart conditions), 2 softgels (200mg) daily may be appropriate under healthcare practitioner guidance. Morning dosing is generally preferred (CoQ10 can be mildly energizing for some people).

Cautions: Consult your healthcare practitioner before use if you take warfarin or other blood thinners (CoQ10 may modestly reduce warfarin effectiveness), are pregnant or breastfeeding, have a heart condition, are scheduled for surgery, or take medication. Effects build over weeks to months; not a fast-acting supplement.

Frequently Asked Questions

➕ Should I take ubiquinone or ubiquinol?
For most adults under 60, ubiquinone (this product) works well and is significantly more accessible. The body converts it to active ubiquinol efficiently. For older adults (60+) or people who've taken ubiquinone without perceived benefit, ubiquinol (SISU Ubiquinol QH 100mg) skips the conversion step — worth trying if you're not getting results from ubiquinone. The research base for ubiquinone is much larger; ubiquinol research is growing.
➕ I'm on a statin — should I take CoQ10?
The case for CoQ10 supplementation during statin use is strong. Statins deplete CoQ10 through their mechanism of action, and CoQ10 supplementation is widely recommended by integrative cardiologists for statin users. Many practitioners now suggest 100–200mg of CoQ10 daily for anyone on long-term statin therapy. Talk to your prescribing practitioner about adding CoQ10 — most cardiologists support the combination, though it's not yet standard prescribing.
➕ How long until I notice effects?
CoQ10 effects build over weeks to months. Energy changes may be noticed in 2–4 weeks for some people. Cardiovascular markers (blood pressure, exercise capacity) typically improve over 4–12 weeks. Don't judge it on a few days. If you've taken 100mg daily for 12 weeks consistently without any perceived benefit, ubiquinol may absorb better for your body chemistry.
➕ Will it interact with my heart medication?
Most heart medications are compatible with CoQ10 supplementation. The main exception is warfarin — CoQ10 may modestly reduce warfarin effectiveness, so dose adjustments and closer INR monitoring may be needed under your practitioner's guidance. Beta-blockers, ACE inhibitors, calcium channel blockers, and statins are typically fine with CoQ10. Always tell your prescribing practitioner what you're taking.
➕ How much should I take daily?
For general maintenance in middle age, 60–100mg daily. For statin support, 100–200mg daily. For heart failure or specific cardiovascular routines, 200–400mg daily under practitioner guidance. The 100mg in this product is the sensible single-softgel daily dose for most uses.
➕ Will it give me energy like caffeine?
No — CoQ10 works at the cellular level rather than as a stimulant. The energy effects are gradual and feel like improved baseline rather than an acute energy boost. Some people notice better stamina, less afternoon fatigue, or improved exercise capacity; others don't "feel" CoQ10 directly even though it's working at the cellular level. It's a foundational support, not a quick energy hit.

Pairs Well With

  • Omega-3 Fish Oils — cardiovascular synergy with CoQ10
  • Magnesium — essential for heart muscle function alongside CoQ10
  • Vitamin D — cardiovascular function support; daily Canadian essential
  • Heart Health Formulas — broader cardiovascular support alongside CoQ10

💡 Subscribe & save up to 10% on every order — never run out of your daily supplements.

Compare Similar Products

  • All CoQ10 Supplements
  • All Heart Health Supplements
  • Energy Support
  • SISU Brand

About Vitamart

Vitamart.ca is Canada's vitamin specialist. We've been selling vitamins and supplements to Canadian families since 2005, shipping from our Ontario warehouse to every province. We believe in quality products you trust at prices you love — no fancy packaging markups, no pushy upsells, just the vitamins you need at the lowest prices in Canada. Backed by our Low Price Guarantee: find a lower advertised price at a Canadian competitor and we'll beat it by 1¢.

Vitamins Lowest Prices.

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SISU Co Q10 100mg Softgels

SISU Co Q10 100mg Softgels Details

SISU Co Q10 100mg Softgels deliver 100mg of ubiquinone CoQ10 — the most-researched form of Coenzyme Q10 with decades of human studies behind it. CoQ10 is essential for cellular energy production in every tissue, with particular concentration in the heart muscle. Production declines with age starting in the 30s–40s, making supplementation increasingly important for cardiovascular health, energy, and antioxidant protection. Particularly important for anyone on statin medications, which deplete CoQ10. SISU sources their CoQ10 from sugar beet fermentation — a clean, vegan-compatible source. Available in 60 or 120 softgels. Made by SISU.

Vitamins Lowest Prices | Lowest Price in Canada — Guaranteed | Ships from Ontario across Canada

Quick Facts

Brand SISU (Canadian)
Form Ubiquinone (most-researched form of CoQ10)
Per softgel 100mg CoQ10
Source Sugar beet fermentation
Sizes 60 or 120 softgels
SISU lineup also 30mg, 60mg, vegetarian capsules, ubiquinol (active form)
Best taken With food containing some fat for absorption

Who SISU Co Q10 100mg Is For

  • Adults 40+ noticing energy decline who want cellular energy support
  • People taking statin medications — statins deplete CoQ10 and supplementation is widely recommended
  • Adults focused on cardiovascular wellness (CoQ10 has strong heart research)
  • People with mild heart conditions wanting natural support alongside medical care
  • Active adults seeking energy and recovery support at the cellular level
  • Anyone with family history of cardiovascular concerns wanting daily preventative support
  • People who want the well-researched ubiquinone form at accessible pricing

Who this product is NOT for: If you're under 35 with no specific reason to take CoQ10, you may not need supplementation — the body produces adequate CoQ10 in younger adults. People on blood thinners (warfarin) should consult their healthcare practitioner; CoQ10 may slightly reduce warfarin effectiveness. Pregnant or breastfeeding women should consult their practitioner. If you specifically want the active reduced form (better absorbed by some), look at ubiquinol products (like SISU Ubiquinol QH 100mg) — higher-priced but may be better for older adults whose conversion is impaired. If you're very price-sensitive, generic CoQ10 products cost less but SISU's quality control is consistent.

Vitamart's Take

CoQ10 is one of the better-researched cardiovascular nutrients, with decades of studies for heart health and energy. Your body makes its own CoQ10, but production drops starting in your 30s — by 80, you have roughly half what you had at 25. SISU's CoQ10 is the workhorse choice: ubiquinone (the most-researched form), 100mg per softgel (the clinical research dose), at one of the better per-softgel costs in Canada. If you're on a statin, this is one of the most important supplements to add — statins deplete CoQ10.

How SISU Co Q10 Compares

SISU Co Q10 (Ubiquinone) vs SISU Ubiquinol QH

Ubiquinone is the oxidized form — most-researched, more accessible, body converts it to active ubiquinol. Ubiquinol is the reduced active form — better absorbed for older adults (60+) or people with impaired conversion. SISU makes both. For adults under 60 with no specific reason for ubiquinol, ubiquinone (this product) is the sensible choice. For older adults or those who haven't responded to ubiquinone, ubiquinol may work better.

SISU Co Q10 100mg vs SISU 30mg or 60mg

SISU makes CoQ10 at three doses (30mg, 60mg, 100mg). 30mg is the maintenance dose for younger adults; 60mg is mid-range; 100mg is the typical therapeutic dose used in heart research and recommended for statin users. Choose based on your goal. For statin support, 100–200mg daily is the research range. For general daily maintenance in middle age, 60–100mg works.

SISU Co Q10 100mg vs Generic CoQ10

Generic CoQ10 (drugstore brands) often uses synthetic CoQ10 at low doses with poor absorption — lower cost but you may absorb minimal active CoQ10. SISU uses naturally-fermented CoQ10 in softgel format with reliable absorption. The cost difference is modest; the absorption difference is meaningful.

SISU Co Q10 vs PQQ

PQQ (pyrroloquinoline quinone) is a related compound sometimes paired with CoQ10 for cellular energy support. PQQ may help create new mitochondria (the cellular energy factories); CoQ10 supports function of existing ones. Different roles. Some advanced cardiovascular routines use both; for most people, CoQ10 alone is the foundation.

What CoQ10 Actually Does

  • Cellular energy production. CoQ10 is essential for the energy-producing machinery in your cells (the mitochondria) that produces ATP — cellular energy. Without CoQ10, energy production stalls. Every cell in your body needs CoQ10; tissues with high energy demands (heart, brain, muscles, kidneys) need the most.
  • Powerful antioxidant. CoQ10 is one of the few antioxidants your body makes natively. It protects cell membranes and LDL cholesterol from oxidative damage. Particularly important for cardiovascular tissues exposed to constant oxidative stress.
  • Production declines with age. The body's ability to make CoQ10 peaks in the 20s and declines steadily. By age 80, you typically have around half the CoQ10 of your younger years. This decline correlates with reduced cellular energy and increased oxidative stress in aging tissues.
  • Heart muscle concentration. Heart muscle has higher CoQ10 concentration than any other tissue in the body — because the heart never stops working and needs constant energy. Cardiovascular research on CoQ10 covers heart failure, blood pressure, post-heart-attack recovery, and statin-related muscle pain.
  • Statin depletion. Statin medications (atorvastatin, simvastatin, rosuvastatin, etc.) block the same biochemical pathway used to make CoQ10. Statin users often have significantly reduced CoQ10, which is implicated in the muscle pain and fatigue some statin users experience. CoQ10 supplementation is widely recommended for statin users by integrative cardiologists.
  • Difficult to get from food. CoQ10 is found in small amounts in beef, peanuts, sardines, and other foods, but the amounts are far below what you'd get from supplementation. Cooking also destroys CoQ10. For meaningful intake, supplementation is the practical approach.
  • Why softgels. CoQ10 is fat-soluble — it absorbs significantly better from oil-based softgels than dry capsules. The softgel format is the gold standard for CoQ10 supplementation.
  • Ubiquinone vs ubiquinol. The body has both forms at the same time — ubiquinone (oxidized) and ubiquinol (reduced/active) — with continuous interconversion. Younger adults convert ubiquinone to ubiquinol efficiently. Older adults and people with certain conditions may have impaired conversion, in which case ubiquinol supplementation skips the conversion step.

How To Use

Adults: Take 1 softgel daily with food containing some fat for best absorption. For higher therapeutic doses (statin support, heart conditions), 2 softgels (200mg) daily may be appropriate under healthcare practitioner guidance. Morning dosing is generally preferred (CoQ10 can be mildly energizing for some people).

Cautions: Consult your healthcare practitioner before use if you take warfarin or other blood thinners (CoQ10 may modestly reduce warfarin effectiveness), are pregnant or breastfeeding, have a heart condition, are scheduled for surgery, or take medication. Effects build over weeks to months; not a fast-acting supplement.

Frequently Asked Questions

➕ Should I take ubiquinone or ubiquinol?
For most adults under 60, ubiquinone (this product) works well and is significantly more accessible. The body converts it to active ubiquinol efficiently. For older adults (60+) or people who've taken ubiquinone without perceived benefit, ubiquinol (SISU Ubiquinol QH 100mg) skips the conversion step — worth trying if you're not getting results from ubiquinone. The research base for ubiquinone is much larger; ubiquinol research is growing.
➕ I'm on a statin — should I take CoQ10?
The case for CoQ10 supplementation during statin use is strong. Statins deplete CoQ10 through their mechanism of action, and CoQ10 supplementation is widely recommended by integrative cardiologists for statin users. Many practitioners now suggest 100–200mg of CoQ10 daily for anyone on long-term statin therapy. Talk to your prescribing practitioner about adding CoQ10 — most cardiologists support the combination, though it's not yet standard prescribing.
➕ How long until I notice effects?
CoQ10 effects build over weeks to months. Energy changes may be noticed in 2–4 weeks for some people. Cardiovascular markers (blood pressure, exercise capacity) typically improve over 4–12 weeks. Don't judge it on a few days. If you've taken 100mg daily for 12 weeks consistently without any perceived benefit, ubiquinol may absorb better for your body chemistry.
➕ Will it interact with my heart medication?
Most heart medications are compatible with CoQ10 supplementation. The main exception is warfarin — CoQ10 may modestly reduce warfarin effectiveness, so dose adjustments and closer INR monitoring may be needed under your practitioner's guidance. Beta-blockers, ACE inhibitors, calcium channel blockers, and statins are typically fine with CoQ10. Always tell your prescribing practitioner what you're taking.
➕ How much should I take daily?
For general maintenance in middle age, 60–100mg daily. For statin support, 100–200mg daily. For heart failure or specific cardiovascular routines, 200–400mg daily under practitioner guidance. The 100mg in this product is the sensible single-softgel daily dose for most uses.
➕ Will it give me energy like caffeine?
No — CoQ10 works at the cellular level rather than as a stimulant. The energy effects are gradual and feel like improved baseline rather than an acute energy boost. Some people notice better stamina, less afternoon fatigue, or improved exercise capacity; others don't "feel" CoQ10 directly even though it's working at the cellular level. It's a foundational support, not a quick energy hit.

Pairs Well With

  • Omega-3 Fish Oils — cardiovascular synergy with CoQ10
  • Magnesium — essential for heart muscle function alongside CoQ10
  • Vitamin D — cardiovascular function support; daily Canadian essential
  • Heart Health Formulas — broader cardiovascular support alongside CoQ10

💡 Subscribe & save up to 10% on every order — never run out of your daily supplements.

Compare Similar Products

  • All CoQ10 Supplements
  • All Heart Health Supplements
  • Energy Support
  • SISU Brand

About Vitamart

Vitamart.ca is Canada's vitamin specialist. We've been selling vitamins and supplements to Canadian families since 2005, shipping from our Ontario warehouse to every province. We believe in quality products you trust at prices you love — no fancy packaging markups, no pushy upsells, just the vitamins you need at the lowest prices in Canada. Backed by our Low Price Guarantee: find a lower advertised price at a Canadian competitor and we'll beat it by 1¢.

Vitamins Lowest Prices.

Product Information

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Description

SISU Co Q10 100mg Softgels Details

SISU Co Q10 100mg Softgels deliver 100mg of ubiquinone CoQ10 — the most-researched form of Coenzyme Q10 with decades of human studies behind it. CoQ10 is essential for cellular energy production in every tissue, with particular concentration in the heart muscle. Production declines with age starting in the 30s–40s, making supplementation increasingly important for cardiovascular health, energy, and antioxidant protection. Particularly important for anyone on statin medications, which deplete CoQ10. SISU sources their CoQ10 from sugar beet fermentation — a clean, vegan-compatible source. Available in 60 or 120 softgels. Made by SISU.

Vitamins Lowest Prices | Lowest Price in Canada — Guaranteed | Ships from Ontario across Canada

Quick Facts

Brand SISU (Canadian)
Form Ubiquinone (most-researched form of CoQ10)
Per softgel 100mg CoQ10
Source Sugar beet fermentation
Sizes 60 or 120 softgels
SISU lineup also 30mg, 60mg, vegetarian capsules, ubiquinol (active form)
Best taken With food containing some fat for absorption

Who SISU Co Q10 100mg Is For

  • Adults 40+ noticing energy decline who want cellular energy support
  • People taking statin medications — statins deplete CoQ10 and supplementation is widely recommended
  • Adults focused on cardiovascular wellness (CoQ10 has strong heart research)
  • People with mild heart conditions wanting natural support alongside medical care
  • Active adults seeking energy and recovery support at the cellular level
  • Anyone with family history of cardiovascular concerns wanting daily preventative support
  • People who want the well-researched ubiquinone form at accessible pricing

Who this product is NOT for: If you're under 35 with no specific reason to take CoQ10, you may not need supplementation — the body produces adequate CoQ10 in younger adults. People on blood thinners (warfarin) should consult their healthcare practitioner; CoQ10 may slightly reduce warfarin effectiveness. Pregnant or breastfeeding women should consult their practitioner. If you specifically want the active reduced form (better absorbed by some), look at ubiquinol products (like SISU Ubiquinol QH 100mg) — higher-priced but may be better for older adults whose conversion is impaired. If you're very price-sensitive, generic CoQ10 products cost less but SISU's quality control is consistent.

Vitamart's Take

CoQ10 is one of the better-researched cardiovascular nutrients, with decades of studies for heart health and energy. Your body makes its own CoQ10, but production drops starting in your 30s — by 80, you have roughly half what you had at 25. SISU's CoQ10 is the workhorse choice: ubiquinone (the most-researched form), 100mg per softgel (the clinical research dose), at one of the better per-softgel costs in Canada. If you're on a statin, this is one of the most important supplements to add — statins deplete CoQ10.

How SISU Co Q10 Compares

SISU Co Q10 (Ubiquinone) vs SISU Ubiquinol QH

Ubiquinone is the oxidized form — most-researched, more accessible, body converts it to active ubiquinol. Ubiquinol is the reduced active form — better absorbed for older adults (60+) or people with impaired conversion. SISU makes both. For adults under 60 with no specific reason for ubiquinol, ubiquinone (this product) is the sensible choice. For older adults or those who haven't responded to ubiquinone, ubiquinol may work better.

SISU Co Q10 100mg vs SISU 30mg or 60mg

SISU makes CoQ10 at three doses (30mg, 60mg, 100mg). 30mg is the maintenance dose for younger adults; 60mg is mid-range; 100mg is the typical therapeutic dose used in heart research and recommended for statin users. Choose based on your goal. For statin support, 100–200mg daily is the research range. For general daily maintenance in middle age, 60–100mg works.

SISU Co Q10 100mg vs Generic CoQ10

Generic CoQ10 (drugstore brands) often uses synthetic CoQ10 at low doses with poor absorption — lower cost but you may absorb minimal active CoQ10. SISU uses naturally-fermented CoQ10 in softgel format with reliable absorption. The cost difference is modest; the absorption difference is meaningful.

SISU Co Q10 vs PQQ

PQQ (pyrroloquinoline quinone) is a related compound sometimes paired with CoQ10 for cellular energy support. PQQ may help create new mitochondria (the cellular energy factories); CoQ10 supports function of existing ones. Different roles. Some advanced cardiovascular routines use both; for most people, CoQ10 alone is the foundation.

What CoQ10 Actually Does

  • Cellular energy production. CoQ10 is essential for the energy-producing machinery in your cells (the mitochondria) that produces ATP — cellular energy. Without CoQ10, energy production stalls. Every cell in your body needs CoQ10; tissues with high energy demands (heart, brain, muscles, kidneys) need the most.
  • Powerful antioxidant. CoQ10 is one of the few antioxidants your body makes natively. It protects cell membranes and LDL cholesterol from oxidative damage. Particularly important for cardiovascular tissues exposed to constant oxidative stress.
  • Production declines with age. The body's ability to make CoQ10 peaks in the 20s and declines steadily. By age 80, you typically have around half the CoQ10 of your younger years. This decline correlates with reduced cellular energy and increased oxidative stress in aging tissues.
  • Heart muscle concentration. Heart muscle has higher CoQ10 concentration than any other tissue in the body — because the heart never stops working and needs constant energy. Cardiovascular research on CoQ10 covers heart failure, blood pressure, post-heart-attack recovery, and statin-related muscle pain.
  • Statin depletion. Statin medications (atorvastatin, simvastatin, rosuvastatin, etc.) block the same biochemical pathway used to make CoQ10. Statin users often have significantly reduced CoQ10, which is implicated in the muscle pain and fatigue some statin users experience. CoQ10 supplementation is widely recommended for statin users by integrative cardiologists.
  • Difficult to get from food. CoQ10 is found in small amounts in beef, peanuts, sardines, and other foods, but the amounts are far below what you'd get from supplementation. Cooking also destroys CoQ10. For meaningful intake, supplementation is the practical approach.
  • Why softgels. CoQ10 is fat-soluble — it absorbs significantly better from oil-based softgels than dry capsules. The softgel format is the gold standard for CoQ10 supplementation.
  • Ubiquinone vs ubiquinol. The body has both forms at the same time — ubiquinone (oxidized) and ubiquinol (reduced/active) — with continuous interconversion. Younger adults convert ubiquinone to ubiquinol efficiently. Older adults and people with certain conditions may have impaired conversion, in which case ubiquinol supplementation skips the conversion step.

How To Use

Adults: Take 1 softgel daily with food containing some fat for best absorption. For higher therapeutic doses (statin support, heart conditions), 2 softgels (200mg) daily may be appropriate under healthcare practitioner guidance. Morning dosing is generally preferred (CoQ10 can be mildly energizing for some people).

Cautions: Consult your healthcare practitioner before use if you take warfarin or other blood thinners (CoQ10 may modestly reduce warfarin effectiveness), are pregnant or breastfeeding, have a heart condition, are scheduled for surgery, or take medication. Effects build over weeks to months; not a fast-acting supplement.

Frequently Asked Questions

➕ Should I take ubiquinone or ubiquinol?
For most adults under 60, ubiquinone (this product) works well and is significantly more accessible. The body converts it to active ubiquinol efficiently. For older adults (60+) or people who've taken ubiquinone without perceived benefit, ubiquinol (SISU Ubiquinol QH 100mg) skips the conversion step — worth trying if you're not getting results from ubiquinone. The research base for ubiquinone is much larger; ubiquinol research is growing.
➕ I'm on a statin — should I take CoQ10?
The case for CoQ10 supplementation during statin use is strong. Statins deplete CoQ10 through their mechanism of action, and CoQ10 supplementation is widely recommended by integrative cardiologists for statin users. Many practitioners now suggest 100–200mg of CoQ10 daily for anyone on long-term statin therapy. Talk to your prescribing practitioner about adding CoQ10 — most cardiologists support the combination, though it's not yet standard prescribing.
➕ How long until I notice effects?
CoQ10 effects build over weeks to months. Energy changes may be noticed in 2–4 weeks for some people. Cardiovascular markers (blood pressure, exercise capacity) typically improve over 4–12 weeks. Don't judge it on a few days. If you've taken 100mg daily for 12 weeks consistently without any perceived benefit, ubiquinol may absorb better for your body chemistry.
➕ Will it interact with my heart medication?
Most heart medications are compatible with CoQ10 supplementation. The main exception is warfarin — CoQ10 may modestly reduce warfarin effectiveness, so dose adjustments and closer INR monitoring may be needed under your practitioner's guidance. Beta-blockers, ACE inhibitors, calcium channel blockers, and statins are typically fine with CoQ10. Always tell your prescribing practitioner what you're taking.
➕ How much should I take daily?
For general maintenance in middle age, 60–100mg daily. For statin support, 100–200mg daily. For heart failure or specific cardiovascular routines, 200–400mg daily under practitioner guidance. The 100mg in this product is the sensible single-softgel daily dose for most uses.
➕ Will it give me energy like caffeine?
No — CoQ10 works at the cellular level rather than as a stimulant. The energy effects are gradual and feel like improved baseline rather than an acute energy boost. Some people notice better stamina, less afternoon fatigue, or improved exercise capacity; others don't "feel" CoQ10 directly even though it's working at the cellular level. It's a foundational support, not a quick energy hit.

Pairs Well With

  • Omega-3 Fish Oils — cardiovascular synergy with CoQ10
  • Magnesium — essential for heart muscle function alongside CoQ10
  • Vitamin D — cardiovascular function support; daily Canadian essential
  • Heart Health Formulas — broader cardiovascular support alongside CoQ10

💡 Subscribe & save up to 10% on every order — never run out of your daily supplements.

Compare Similar Products

  • All CoQ10 Supplements
  • All Heart Health Supplements
  • Energy Support
  • SISU Brand

About Vitamart

Vitamart.ca is Canada's vitamin specialist. We've been selling vitamins and supplements to Canadian families since 2005, shipping from our Ontario warehouse to every province. We believe in quality products you trust at prices you love — no fancy packaging markups, no pushy upsells, just the vitamins you need at the lowest prices in Canada. Backed by our Low Price Guarantee: find a lower advertised price at a Canadian competitor and we'll beat it by 1¢.

Vitamins Lowest Prices.